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If it's 1:1 with coke then recrystallization would be difficult. Anyone have a clue as to how much Levmisole is typically used as a cutting agent? If it's 1:1, 2:1, 3:1 etc. This could be problematic since cocaine has two esters that are also susceptible to alkaline hydrolysis and trying to find conditions to selectively hydrolyze Levamisole in the presence of cocaine without destroying the cocaine would require experimentation and a good analytic equipment to make sure the cocaine has survived. (Though I personally don't have too much experience with thioamidines). I'm thinking that any mild base (bicarbonate, carbonate etc.) used to freebase coke might not be harsh enough to hydrolyze the thioamidine in Levamisole without heating/prolonged reaction time. Chloroform is not that hard to come by either. Maybe someone could chip in with info as to whether cocaine solubility in chloroform is sufficient for chloroform to be used.Īfter all, drenching your blow in enough chloroform to dissolve all the blow, filtering out the particulates and leaving to evaporate is no big deal. Levamisole is considered 'slightly soluble' in chloroform. It seems that chloroform could be a suitable purification solvent. OK, I'm talking to myself but I think this is important. Question: are the hydrolisis products harmless? Here's the source of the quotation. This would mean that by basing your blow you hydrolyze (=destroy) the Levamisol. Ethanol is a possible solvent for purification.īut what I'm most interested in is the fact that it hydrolyzes in alkaline (or neutral) solutions.
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This is what I read on the web: 'The hydrochloride salt of levamisole is a white crystalline powder with odorless soluble in water and methanol slightly soluble in ethanol and methylene chloride insoluble in ether stable in acid aqueous media but hydrolyzes in alkaline (or neutral) solutions.' Ether is impossible to get rid of these days so let's forget about it.
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